Welcome to the UVC LED Disinfection Group at DTU
Catheter-related infections caused by bacterial growth in long-term catheters are responsible for substantial morbidity and mortality, and impose a heavy burden on healthcare systems worldwide. It is generally accepted that biofilms form shortly after catheter placement and that biofilm formation is the basis for catheter-related infection. Therefore, methods that can prevent or eradicate catheter biofilms are of substantial clinical interest.
Bacteria can be killed by ultraviolet light (UV) exposure. The most germicidal part of UV spectrum, designated UVC, occurs at wavelengths below 280 nm. UVC light exposure has been used for decades for disinfecting drinking water. Ultraviolet light is not specific against selected bacteria and can in principle be used to kill all pathogens with the use of slightly different doses.
Newly developed UVC light sources based on light emitting diodes (LED) technology combined with appropriate lens systems are very applicable for disinfecting tube lumens due to the fact that almost all light emitted from the light source can be launched directly into the tube lumen.
Our group has demonstrated that UVC light from LEDs can be launched into and transmitted through tubes made of teflon, polyurethane and silicone. In addition, the results obtained by using UVC light exposure on Pseudomonas aeruginosa contaminated polymer tubes reveals that a technical solution based on UVC light for catheter disinfection can be reached in near future.