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| Title:
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Model visualization for evaluation of biocatalytic processes |
| Type:
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Journal articleJournal article |
| Participant(s):
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Forfatter:
Law, HEM
University College London, Department of Biochemical Engineering
Forfatter:
Lewis, DJ
Innospec Ltd.
Forfatter:
McRobbie, I
Innocpec Ltd.
Technical University of Denmark
Email:
Redaktør:
Gernary, Krist V.
Technical University of Denmark
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| Abstract:
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Biocatalysis offers great potential as an additional, and in some cases as an alternative, synthetic tool for organic chemists, especially as a route to introduce chirality. However, the implementation of scalable biocatalytic processes nearly always requires the introduction of process and/or biocatalyst enhancements to ensure effective scale-up. This paper describes a paradigm for the purpose of evaluating biocatalytic processes in order to provide guidance on process and biocatalyst modification. The paradigm is illustrated with the biocatalytic synthesis of S,S-ethylenediaminedisuccinic acid (S,S-EDDS), a biodegradable chelant, and is characterised by the use of model visualization using `windows of operation". |
| Published:
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in journal: Food and Bioproducts Processing (ISSN: 0960-3085) (DOI: http://dx.doi.org/10.1016/j.fbp.2008.03.006), vol: 86, issue: 2, pages: 96-103, 2008 |
| DOI:
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